March 31 and April 1, 2009
Cincinnati, Ohio
©2009 Girindus America, Inc.
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Day 1 Presentations
Manufacturing Therapeutic Oligonucleotides; Lessons Learned from Macugen (PDF)
Fran Wincott Ph.D
Wincott & Associates, LLC
Synthesis of RNA and Nucleic Acid Analogs – The Next Chapters (PDF)
Marv Caruthers
University of Colorado
DNA and RNA Mimetics: Oligonucletide N3’ › P5’ Phosphoramidates (PDF)
Sergei M. Gryaznov, Ph.D
Director & Sr. Research Fellow, Nucleic Acid Chemistry
Geron Corp
Locked Nucleic Acid:
From discovery to first dose in man from a chemistry perspective (PDF)
Christoph Rosenbohm, PhD, MBA
santoris pharma
Mass Spectrometry Challenges for ODN Therapeutics (PDF)
Pat Limbach
Rieveschl Laboratories for Mass Spectrometry, Department of Chemistry
University of Cincinnati
Phosphorothiate oligonucleotides as amphipathic polymers (PDF)
Dr. Andrew Vaillant
VP, CSO
REPLICor
Oligonucleotide Manufacturing at Girindus (PDF)
Girindus Solvay Organics
Day 2 Presentations
Nucleotide Synthesis, The First Forty Years, 1950 - 1990 (PDF)
Kelvin Ogilivie
Acadia University
Modifying DNA’s building blocks: Insights in nucleic acid structure and development of DNA/RNA therapeutics (PDF)
Masad J. Damha
McGill University
TIDES 2009 Poster
Girindus Solvay Organics